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Search Results for " transforming growth factor, beta receptor ii "

Targets

2

Compounds

32

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
T6337 RepSox ALK5 Inhibitor II,SJN 2511,E-616452 ALK , TGF-beta/Smad
RepSox (ALK5 Inhibitor II) is a TGFβR-1/ALK5 inhibitor that selectively inhibits the binding of ATP to ALK5 and the autophosphorylation of ALK5 (IC50=23/4 nM). RepSox induces adipogenesis in MEFs cells.
T22560 ALK5 Inhibitor II (hydrochloride) Others
ALK5 Inhibitor II is an ALK5 inhibitor. IC50: 4, 18, and 23 nM for ALK5 autophosphorylation, TGF-β cellular assay, and ALK5 binding in HepG2 cells, respectively.

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPJ-00335 TGFBR2 Protein, Mouse, Recombinant (His) Mouse Human Cells
Transforming growth factor-β (TGF-β) is an essential regulator in the processes of development, cell proliferation, and extracellular matrix deposition. TGF-β regulates cellular processes by binding to three high-affinit...
TMPY-05157 TGFBR2 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
TGFBR2 is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. It is a transmembrane protein. TGFBR2 is comprised of a C-terminal protein kinase domain and an N-terminal ectodomain. The ectodoma...
TMPY-03082 TGFBR2 Protein, Rat, Recombinant (hFc) Rat HEK293
TGFBR2 is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. It is a transmembrane protein. TGFBR2 is comprised of a C-terminal protein kinase domain and an N-terminal ectodomain. The ectodoma...
TMPY-03171 TGFBR2 Protein, Rhesus, Recombinant (hFc) Rhesus HEK293
TGFBR2 is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. It is a transmembrane protein. TGFBR2 is comprised of a C-terminal protein kinase domain and an N-terminal ectodomain. The ectodoma...
TMPJ-00334 TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc) Mouse Human Cells
Transforming growth factor-β (TGF-β) is an essential regulator in the processes of development, cell proliferation, and extracellular matrix deposition. TGF-β regulates cellular processes by binding to three high-affinit...
TMPJ-00333 TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc) Mouse Human Cells
Transforming growth factor-β (TGF-β) is an essential regulator in the processes of development, cell proliferation, and extracellular matrix deposition. TGF-β regulates cellular processes by binding to three high-affinit...
TMPY-05810 TGFBR2 Protein, Human, Recombinant (His & hFc), Biotinylated Human HEK293
TGFBR2 is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. It is a transmembrane protein. TGFBR2 is comprised of a C-terminal protein kinase domain and an N-terminal ectodomain. The ectodoma...
TMPY-05508 TGFBR2 Protein, Human, Recombinant (hFc) Human HEK293
TGFBR2 is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. It is a transmembrane protein. TGFBR2 is comprised of a C-terminal protein kinase domain and an N-terminal ectodomain. The ectodoma...
TMPY-01168 ALK-1 Protein, Human, Recombinant (His) Human HEK293
Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (transforming growth factor beta) receptor family of ligands. ...
TMPJ-00261 TGF beta 2 Protein, Mouse/Rat, Recombinant Mouse,Rat Human Cells
Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deletion show defects in development of cardiac, lung, craniofaci...
TMPJ-00254 TGF beta 3 Protein, Human/Mouse/Rat, Recombinant Human,Mouse,Rat Human Cells
Transforming growth factor beta 3(TGFB3) is a member of a TGF -β superfamily which is defined by theirstructural and functional similarities. TGFB3 is secreted as a complex with LAP. This latent form of TGFB3becomes acti...
TMPY-01059 BMPR2 Protein, Human, Recombinant (His) Human HEK293
The bone morphogenetic protein type II receptor (BMPR-II, or BMPR2), a receptor for the transforming growth factor (TGF)-beta/bone morphogenetic protein (BMP) superfamily. Reduced expression or function of BMPR2 signalin...
TMPY-00662 ALK-1 Protein, Mouse, Recombinant (His & hFc) Mouse HEK293
Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (transforming growth factor beta) receptor family of ligands. ...
TMPJ-00256 Latent TGF-beta 3 Protein, Human, Recombinant (His & Avi), Biotinylated Human Human Cells
Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell type, developmental stage, or tissue conditions. There are...
TMPJ-00255 TGF beta 3 Protein, Human, Recombinant (Avi), Biotinylated Human Human Cells
Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell type, developmental stage, or tissue conditions. There are...
TMPY-03678 ALK-1 Protein, Canine, Recombinant (hFc) Canine HEK293
Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (transforming growth factor beta) receptor family of ligands. ...
TMPY-03315 ALK-1 Protein, Cynomolgus, Recombinant (hFc) Cynomolgus HEK293
Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (transforming growth factor beta) receptor family of ligands. ...
TMPY-00757 ALK-1 Protein, Rat, Recombinant (His & hFc) Rat HEK293
Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (transforming growth factor beta) receptor family of ligands. ...
TMPY-00310 ALK-1 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (transforming growth factor beta) receptor family of ligands. ...
TMPY-00650 ALK-1 Protein, Human, Recombinant (hFc) Human HEK293
Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (transforming growth factor beta) receptor family of ligands. ...
TMPJ-00771 TGF beta 1 Protein, Mouse/Rat, Recombinant Mouse,Rat Human Cells
Transforming growth factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differen...
TMPJ-00315 ACVR2A Protein, Human, Recombinant (hFc & His) Human Human Cells
Activin Receptor Type-2A is a protein that in humans is encoded by the ACVR2A gene. ACVR2A is an activin type 2 receptor. This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation fact...
TMPJ-00314 ACVR2B Protein, Human, Recombinant (hFc & His) Human Human Cells
Activin proteins that belong to the transforming growth factor-beta (TGF-β) superfamily, exert their biological actions by binding to heteromeric receptor complexes of type I and type II serine/threonine kinase receptors...
TMPY-04366 ALK-5 Protein, Human, Recombinant (aa 200-503, His & GST) Human Baculovirus-Insect Cells
Transforming growth factor, beta receptor I, also known as Transforming growth factor-beta receptor type I , Serine / threonine-protein kinase receptor R4, Activin receptor-like kinase 5, SKR4, ALK-5, and TGFBR1, is a si...
TMPY-05771 ALK-5 Protein, Human, Recombinant (hFc) Human HEK293
Transforming growth factor, beta receptor I, also known as Transforming growth factor-beta receptor type I , Serine / threonine-protein kinase receptor R4, Activin receptor-like kinase 5, SKR4, ALK-5, and TGFBR1, is a si...
TMPY-01358 ALK-5 Protein, Human, Recombinant (His & hFc) Human HEK293
Transforming growth factor, beta receptor I, also known as Transforming growth factor-beta receptor type I , Serine / threonine-protein kinase receptor R4, Activin receptor-like kinase 5, SKR4, ALK-5, and TGFBR1, is a si...
TMPY-01764 BMPR1A/ALK-3 Protein, Human, Recombinant (His) Human HEK293
Activin receptor-Like Kinase 3 (ALK-3), also known as Bone Morphogenetic Protein Receptor, type IA (BMPR1A), is a type I receptor for bone morphogenetic proteins (BMPs) which belong to the transforming growth factor beta...
TMPY-05485 BMPR1A/ALK-3 Protein, Human, Recombinant (hFc) Human HEK293
Activin receptor-Like Kinase 3 (ALK-3), also known as Bone Morphogenetic Protein Receptor, type IA (BMPR1A), is a type I receptor for bone morphogenetic proteins (BMPs) which belong to the transforming growth factor beta...
TMPY-01374 BMPR1A/ALK-3 Protein, Mouse, Recombinant (His) Mouse HEK293
Activin receptor-Like Kinase 3 (ALK-3), also known as Bone Morphogenetic Protein Receptor, type IA (BMPR1A), is a type I receptor for bone morphogenetic proteins (BMPs) which belong to the transforming growth factor beta...
TMPY-00962 BMPR1A/ALK-3 Protein, Mouse, Recombinant (His & hFc) Mouse HEK293
Activin receptor-Like Kinase 3 (ALK-3), also known as Bone Morphogenetic Protein Receptor, type IA (BMPR1A), is a type I receptor for bone morphogenetic proteins (BMPs) which belong to the transforming growth factor beta...
TMPY-00614 BMPR1A/ALK-3 Protein, Canine, Recombinant (hFc) Canine HEK293
Activin receptor-Like Kinase 3 (ALK-3), also known as Bone Morphogenetic Protein Receptor, type IA (BMPR1A), is a type I receptor for bone morphogenetic proteins (BMPs) which belong to the transforming growth factor beta...
TMPY-00683 BMPR2 Protein, Human, Recombinant (His & hFc) Human HEK293
The bone morphogenetic protein type II receptor (BMPR-II, or BMPR2), a receptor for the transforming growth factor (TGF)-beta/bone morphogenetic protein (BMP) superfamily. Reduced expression or function of BMPR2 signalin...
TGFBR2 Protein, Mouse, Recombinant (His)
TMPJ-00335
Species: Mouse
Expression System: Human Cells
TGFBR2 Protein, Human, Recombinant (His)
TMPY-05157
Species: Human
Expression System: Baculovirus-Insect Cells
TGFBR2 Protein, Rat, Recombinant (hFc)
TMPY-03082
Species: Rat
Expression System: HEK293
TGFBR2 Protein, Rhesus, Recombinant (hFc)
TMPY-03171
Species: Rhesus
Expression System: HEK293
TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc)
TMPJ-00334
Species: Mouse
Expression System: Human Cells
TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc)
TMPJ-00333
Species: Mouse
Expression System: Human Cells
TGFBR2 Protein, Human, Recombinant (His & hFc), Biotinylated
TMPY-05810
Species: Human
Expression System: HEK293
TGFBR2 Protein, Human, Recombinant (hFc)
TMPY-05508
Species: Human
Expression System: HEK293
ALK-1 Protein, Human, Recombinant (His)
TMPY-01168
Species: Human
Expression System: HEK293
TGF beta 2 Protein, Mouse/Rat, Recombinant
TMPJ-00261
Species: Mouse,Rat
Expression System: Human Cells
TGF beta 3 Protein, Human/Mouse/Rat, Recombinant
TMPJ-00254
Species: Human,Mouse,Rat
Expression System: Human Cells
BMPR2 Protein, Human, Recombinant (His)
TMPY-01059
Species: Human
Expression System: HEK293
ALK-1 Protein, Mouse, Recombinant (His & hFc)
TMPY-00662
Species: Mouse
Expression System: HEK293
Latent TGF-beta 3 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPJ-00256
Species: Human
Expression System: Human Cells
TGF beta 3 Protein, Human, Recombinant (Avi), Biotinylated
TMPJ-00255
Species: Human
Expression System: Human Cells
ALK-1 Protein, Canine, Recombinant (hFc)
TMPY-03678
Species: Canine
Expression System: HEK293
ALK-1 Protein, Cynomolgus, Recombinant (hFc)
TMPY-03315
Species: Cynomolgus
Expression System: HEK293
ALK-1 Protein, Rat, Recombinant (His & hFc)
TMPY-00757
Species: Rat
Expression System: HEK293
ALK-1 Protein, Cynomolgus, Recombinant (His)
TMPY-00310
Species: Cynomolgus
Expression System: HEK293
ALK-1 Protein, Human, Recombinant (hFc)
TMPY-00650
Species: Human
Expression System: HEK293
TGF beta 1 Protein, Mouse/Rat, Recombinant
TMPJ-00771
Species: Mouse,Rat
Expression System: Human Cells
ACVR2A Protein, Human, Recombinant (hFc & His)
TMPJ-00315
Species: Human
Expression System: Human Cells
ACVR2B Protein, Human, Recombinant (hFc & His)
TMPJ-00314
Species: Human
Expression System: Human Cells
ALK-5 Protein, Human, Recombinant (aa 200-503, His & GST)
TMPY-04366
Species: Human
Expression System: Baculovirus-Insect Cells
ALK-5 Protein, Human, Recombinant (hFc)
TMPY-05771
Species: Human
Expression System: HEK293
ALK-5 Protein, Human, Recombinant (His & hFc)
TMPY-01358
Species: Human
Expression System: HEK293
BMPR1A/ALK-3 Protein, Human, Recombinant (His)
TMPY-01764
Species: Human
Expression System: HEK293
BMPR1A/ALK-3 Protein, Human, Recombinant (hFc)
TMPY-05485
Species: Human
Expression System: HEK293
BMPR1A/ALK-3 Protein, Mouse, Recombinant (His)
TMPY-01374
Species: Mouse
Expression System: HEK293
BMPR1A/ALK-3 Protein, Mouse, Recombinant (His & hFc)
TMPY-00962
Species: Mouse
Expression System: HEK293
BMPR1A/ALK-3 Protein, Canine, Recombinant (hFc)
TMPY-00614
Species: Canine
Expression System: HEK293
BMPR2 Protein, Human, Recombinant (His & hFc)
TMPY-00683
Species: Human
Expression System: HEK293
Cat No. Product Name
L4100 TGF-beta/Smad Compound Library

184 compounds
A unique collection of 184 TGF-beta/Smad signaling targeted compounds for high throughput and high content screening;
TargetMol